We are a service provider for recombinant antibody production. We offer recombinant antibodies (including bispecific and fusion antibodies), afucosylated antibodies for increased ADCC activity and other proteins.
We only offer expression in CHO, as CHO cells are used for most of the currently approved biotherapeutics. Antibody production in CHO cell cultures enables faster turnaround times, greater yields and significant quality advantages of the antibodies produced in contrast to conventional, out-dated production methods.
We are very flexible and can produce any volume starting at 50ml or quantity from 1mg to multiple grams.
We cannot guarantee a typical % but we see >95% monomericity in vast majority of the cases (for standard antibodies). We do inform customers if we see more than 5% aggregates and then sometimes perform a SEC purification based on their agreement.
We guarantee a low level of endotoxin (<1 EU/mg).
Protein A purification is standard and we use alternative resins such as Protein G, L, Kappa/Lambda-Select or anti-IgG-CH1 as needed. An additional size exclusion chromatography (SEC) purification step can be added. Please inquire for more details.
Standard analytics include antibody purity, quantification, concentration and guaranteed low endotoxin levels. Additional services include, but not limited to, mass spec and SDS-PAGE. Please inquire if you have specific requirements.
Our average timeline is between 6 and 7 weeks for the production of new antibodies. We do guarantee 6-8 weeks from amino acid sequence to purified antibody with our standard services and 5-6 weeks with our RUSH offering. If we have produced the antibody before then reproduction will take 1-4 weeks.
Currently, all production is in Zurich, Switzerland and we can ship globally via Fedex or with alternative providers.
We have produced both bispecific antibodies and trispecific antibodies in various formats. Please contact your local evitria representative to discuss your specific project.
Pricing can vary depending on project specifics. Please contact your local evitria representative to discuss.
No, but please see our “Partners” page to find best-in-class solutions for required services.
No, but please see our “Partners” page to find best-in-class solutions for required services.
Yes, we can help! Please contact your local evitria representative to discuss your specific needs.
We have been supporting customers globally from academia, biotech start-ups, virtual companies, diagnostic companies, large biopharma and more.
We have optimized our system over the last 11 years to work best and have experienced a reduction in expression levels when using any outside plasmids. However, we can discuss on a case-to-case basis so please inquire.
We are unable to send our proprietary vectors but can clone into a freedom-to-use vector and send for an additional fee.