evitria is your expert when it comes to the custom production of antibodies for research, industrial and small-scale applications.
We are specialized in recombinant antibody production in CHO cells. This allows us to produce immunoglobulins with high batch-to-batch consistency, low endotoxin levels and at high speed.
We believe that high-quality antibodies pay off at every stage of your project.
Our antibody production services include:
Antibody production runs
Antibodies purified
Projects completed on time
From Sequence to Antibody
evitria AG produces custom recombinant antibodies and standard positive and negative antibody controls to meet your specific needs or requirements. This can involve the production of a new antibody that is not currently available on the market or the customization of an existing antibody to better fit your needs.
Our CHO cell line allows us to perform recombinant antibody expression in shorter timelines and with higher yields than possible with traditional, out-dated methods.
Overview:
We use Chinese Hamster Ovary (CHO) cells as our expression platform of choice for recombinant antibody production. They enable us to express antibodies in large amounts, in high quality and low endotoxin levels (<1 EU/mg), with or without afucosylation.
Having performed more than 120,000 production runs, expressed more than 23,000 proteins and purified more than 20,000 antibodies since 2010, we have been providing our products to customers around the globe – from academic laboratories and small biotech start-ups to global biopharma companies.
When choosing evitria as your provider of recombinant antibody production services, you profit from our profound expertise in fields like
Our efficient workflow in antibody production allows us to provide you with high quality antibodies within 5 weeks from sequence to shipment.
From sequence to antibody in 5 weeks
Project start
0-1 business days
Pilot study
(from electronic sequence to quantified pilot supernatant)
15-20 business days
Larger-scale expression
5-10 business days
Purification
2-3 business days
Final analytics
2-3 business days
Shipment
1-2 business days
Antibody development and quality control by mass spectometry
No, evitria does not use live animals for antibody production, and neither are E. Coli or HEK cells used. Instead, we rely on CHO cells as a mammalian expression system, as this comes with several advantages.
Protein A purification is standard and, as needed, we use alternative resins such as Protein G, L, Kappa/Lambda-Select or anti-IgG-CH1. An additional size exclusion chromatography (SEC) purification step can be added. Please contact us for more details.
For new antibodies, our average timeline is between 6 and 7 weeks. With our standard services, we do guarantee 6-8 weeks from amino acid sequence to purified antibody and 5-6 weeks with our RUSH offering. If we have produced the antibody before, reproduction will take 1-2 weeks.