Antibodies Journal
Explore evitria’s Antibody Journal for in-depth articles on antibody engineering, CHO cell expression systems, and advancements in recombinant antibody production services.
Articles about Antibodies Journal (2)
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HEK293 cells vs. CHO cells
HEK cells, also known as HEK293, are human embryonic kidney cells which grow in tissue culture and represent a distinct immortalised cell line. Although HEK cells and CHO cells are both used to create antibodies and for therapeutic protein production, they differ in many aspects, which will be discussed later in this article.
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Antibody production in CHO cells: Advantages & Disadvantages
CHO cells are an essential tool in antibody production. But why should one choose CHO cells instead of other expression systems? Read more to find out!
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CHO cells – 7 facts about the cell line derived from the ovary of the Chinese hamster
Cells derived from animals like Chinese hamster ovary cells have been cultured and manipulated for use in pharmaceutical compounds for decades. They form the vital basis of a vast number of applications and are perfect tools for research and development.
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Therapeutic antibodies: afucosylated antibodies with enhanced antibody-dependent cellular cytotoxicity (ADCC)
Therapeutic antibodies are the fastest-growing class of biological drugs. Their ability to interact with specific targets means they can be employed for a range of diseases, including cancer, autoimmune and infectious diseases.
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7 reasons for us to choose Chinese hamster ovary (CHO) cells for recombinant protein production
In this article, we will discuss 7 reasons why we at evitria use CHO cells in recombinant protein production.
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HEK293 cells for recombinant antibody production
HEK cells are intensely used in applications like recombinant antibody production. Why? Find out in this article!
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Antibody-Dependent Cellular Cytotoxicity (ADCC) – Definition, Mechanism & Application
Antibody-dependent cellular cytotoxicity is a key process of the immune system’s arsenal to ward off cancerous cells and infections. We show you important definitions and the ADCC mechanism and key facts on ADCC antibodies in this post.
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Monoclonal antibody production: Process, Technologies & Steps
Monoclonal antibodies play a significant role in different fields of life sciences and medicine. But how are they produced in the first place?
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Why Recombinant DNA Construct Design Determines Protein and Antibody Expression Success
A sequence-correct recombinant DNA construct can still fail during protein expression. Learn how cloning strategy, vector architecture, signal peptides and CHO-cell design influence antibody yield, assembly and quality.
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What is the Typical Turnaround Time for HTP Antibody Production?
evitria’s HTP Antibody Production Service delivers purified, analytics-confirmed material within a 4-week cycle from sequence approval. Learn what factors influence turnaround time and how to plan your screening campaign effectively.
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Developability-by-Design: The 5 Readouts to Check Before Picking Winners
Identifying a high-affinity binder is only the first hurdle in antibody discovery. Developability-by-Design integrates five key biophysical readouts into the selection process to ensure only manufacturable candidates advance.
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Why HTP Screening Results Sometimes Fail to Translate to Manufacturing
Top-tier HTP screening leads frequently fail to translate to manufacturing due to host system incompatibilities and production artefacts. This article examines the root causes and how to close the translation gap.
