Custom Antibody Production in CHO Cells
From recombinant IgGs to bispecific, afucosylated, Fc-silenced and high-throughput formats. 140,000+ production runs for biotech and pharma worldwide.
All projects begin within 24 hours of your approval, with lightning-fast completion times.
Our Custom Antibody Production Services
evitria is your partner for custom antibody production in CHO cells. Our expertise covers the full spectrum from early discovery through larger scale in vivo studies.
- Recombinant Antibody Expression Service: standard IgG production
- Bispecific Antibody Production Service: dual-targeting formats
- Afucosylated Antibody Service: enhanced ADCC and increased effector function
- Fc-Silenced Antibody Production Service: reduced effector function
- High-Throughput Antibody Production Service: parallel expression of a large number of constructs
- Other Recombinant Protein Expression Service: non-antibody soluble proteins, such as antigens or alternative scaffolds
Our Solutions
Antibody Production Tailored to Your Specific Field
Flexibility, expertise & access to innovation
Reliable outcomes in antibody development depend on flexible collaboration, deep know-how, and access to the right technologies.
With license agreements like GlymaxX®, Opti-mAb®, and STR, you can easily integrate advanced functionalities into your constructs, without added complexity or delays.
Introducing: High-Throughput Antibody Production
Screen more candidates, decide faster. evitria’s CHO-based HTP antibody production service expresses up to several hundred antibody constructs in parallel, delivering purified, assay-ready material in as little as 4 weeks.
Designed for AI-driven discovery and optimization pipelines, early-stage screening, or later-stage protein engineering and humanization campaigns that demand speed without compromising quality.
Expression Services
Recombinant antibodies for discovery and development
Afucosylated Antibody Expression Service
Accelerate your therapeutic research with our high-quality afucosylated antibody expression service.
Fc-Silenced Antibody Expression Service
Achieve zero immune activation – with our expression service for truly Fc-silenced antibodies.
Bispecific Antibody Production Service
More than one target? Hit them all – we’ll support you with our bispecific antibody expression service!
Recombinant Protein Expression Service
Discover high-quality, reliable protein expression services at evitria.
Recombinant Antibody Expression Service
Take in your project to the next level – with high-quality recombinant antibody expression services at evitria.
High-Throughput Antibody Production Service
Up to several hundred constructs in parallel, >95% purity, <4 weeks turnaround, CHO-expressed and assay-ready.
Upcoming Events 2026
-
September
1
hubXchange Antibody Manufacturing – San Francisco
San Francisco
-
October
13 – 15
Festival of Biologics Europe
Basel
-
November
17 – 19
PEGS Europe 2026
Lisbon
Global presence –
local touch
Headed near Zurich, Switzerland, our global presence has expanded worldwide. This allows us to stay in close contact with all our customers around the globe – for straightforward and easy communication on your project.
Contact our experts: contact@evitria.com
Recommended articles
Dive into our Antibody Journal for expert insights on recombinant antibody expression, CHO cells, and bispecific antibodies.
-
Antibody-Dependent Cellular Cytotoxicity (ADCC) – Definition, Mechanism & Application
Antibody-dependent cellular cytotoxicity is a key process of the immune system’s arsenal to ward off cancerous cells and infections. We show you important definitions and the ADCC mechanism and key facts on ADCC antibodies in this post.
-
Afucosylated recombinant antibodies
Generally speaking, antibodies of any kind, including recombinant and afucosylated antibodies, are Y-shaped proteins produced by the human body. As they are able to identify and neutralize foreign objects – in other words viruses – they play a major contributing role in keeping our body and immune system healthy.
-
Recombinant Antibodies – 7 key insights to rAbs
From the application in medicine and science to recombinant antibody production and the advantages of recombinant Abs in contrast to traditional monoclonal antibodies, this article will teach you all you need to know about recombinant antibodies.
-
High-Throughput Antibody Production: A Guide to Workflows, Platforms, and Decision-Ready Data
Complete guide to High-Throughput Antibody Production: CHO-native workflow, developability screening, and decision-grade material in 4 weeks.
FAQs about evitria’s Custom Antibody Production
Custom antibody production is the made-to-order development and manufacture of antibodies tailored to a specific target, format and application. At evitria, scientific consulting is part of the service from start to finish: our team helps you select the right format, expression strategy and engineering options so the antibody setup fits your program from day one.
evitria’s custom monoclonal antibody production service delivers recombinant monoclonal antibodies (mAbs) produced entirely in CHO cells, without the use of living animal hosts. From sequence to purified protein, standard projects are completed in as little as 4 weeks.
The service covers vector preparation, transient CHO transfection, protein A purification and quality control. Optional technology enhancements are available: GlymaxX® optimizes ADCC activity through glycoengineering, and Opti-mAb® stabilizes scFv-containing constructs for bispecific formats. All production is designed for research and development applications.
evitria produces standard recombinant IgGs, bispecific and trispecific antibodies, afucosylated formats for enhanced ADCC, Fc-silenced antibodies with reduced effector function, high-throughput discovery panels and non-antibody proteins. All formats run on CHO-based transient expression.
CHO (Chinese Hamster Ovary) cells are the industry standard for therapeutic antibody production. They provide eukaryotic post-translational modifications, fold complex antibodies correctly and produce high yields at scale. Transient CHO expression allows rapid turnaround from sequence to purified protein within weeks.
Standard turnaround for transient antibody production at evitria starts at four weeks from sequence to delivered protein. Timelines vary by format and quantity: standard IgGs are fastest, bispecifics and complex formats add time for pairing and purification. Clear timelines come upfront after scope discussion.
Pricing depends on your antibody format, production scale, timeline and quality requirements. evitria provides a tailored quote within a few working days after project scope discussion. Get in touch to share your sequence and requirements.
Yes. evitria delivers custom antibodies to biotech and pharma customers in North America, Europe, Asia-Pacific and beyond. Our Swiss production facility uses validated cold-chain logistics to ensure protein integrity from packaging to arrival at your lab.
Standard recombinant production involves stable, full-length chains, whereas many bispecific formats rely on scFvs (single-chain variable fragments), which are notoriously unstable and prone to poor folding. evitria’s bispecific antibody production service addresses this by using Opti-mAb® technology to molecularly stabilize these fragments. This results in significantly higher titers (up to 37x higher yields) and ensures >95% purity, transforming complex, “unmanufacturable” constructs into viable candidates within a 4-week turnaround.
Afucosylated antibodies have enhanced antibody-dependent cellular cytotoxicity (ADCC) and are often used in oncology programs. Fc-silenced antibodies have reduced effector function and are used when immune activation needs to be avoided, for example in checkpoint modulation or payload delivery. evitria produces both formats through dedicated afucosylated antibody expression service and fc-silenced antibody expression service workflows.