Technology spotlight – Learn how the integrated GlymaxX® technology enhances ADCC activity without altering the amino acid sequence of your antibody.
Summary
There are many ways to enhance ADCC by Fc engineering, but these require changing the amino acid sequence of your antibody – a big risk in any therapeutic development project. Afucosylation, i.e. the removal of core fucose residues from antibody glycan structures, is a
way of enhancing ADCC without any amino acid substitutions. At evitria, we combine ProBioGen’s proprietary cell engineering approach, GlymaxX®, with our transient CHO antibody expression platform to rapidly deliver high quality afucosylated antibodies.
Download full technology spotlight now.
