evitria is your expert when it comes to the custom production of recombinant antibodies for research, industrial and small-scale applications.
We are specialized in transient antibody production in CHO cells. This allows us to produce immunoglobulins with high batch-to-batch consistency, low endotoxin levels and at high speed.
We believe that high-quality antibodies pay off at every stage of your project.
Our recombinant antibody expression services include:
Antibody production runs
Antibodies purified
Projects completed on time
From Sequence to Antibody
evitria AG has a single focus on the expression of recombinant antibodies since its foundation in 2010 and is one of the leading service providers in this field.
Having performed more than 120,000 production runs, expressed more than 23,000 proteins and purified more than 20,000 antibodies since 2010, we have been providing our products to customers around the globe – from academic laboratories and small biotech start-ups to global biopharma companies.
Overview:
Our CHO-based expression platform allows us flexible scalability to supply companies in discovery research and commercial manufacturing. Recombinant formats support batch-to-batch consistency. With CHO cell antibody production, we are able to offer recombinant antibodies in large scales with very low levels of endotoxins (<1 EU/mg).
Furthermore, expression in CHO cells can be much faster than in comparable cell lines. From sequence to antibody within 5 weeks is our goal, which we can meet in 99% of all projects.
When choosing evitria as your provider of recombinant antibody production services, you profit from our profound expertise in fields like
Our efficient workflow in antibody production allows us to provide you with high quality antibodies within 5 weeks from sequence to shipment.
From sequence to antibody in 5 weeks
Project start
0-1 business days
Pilot study
(from electronic sequence to quantified pilot supernatant)
15-20 business days
Larger-scale expression
5-10 business days
Purification
2-3 business days
Final analytics
2-3 business days
Shipment
1-2 business days
Antibody development and quality control by mass spectometry
No, evitria does not use live animals for antibody production, and neither are E. Coli or HEK cells used. Instead, we rely on CHO cells as a mammalian expression system, as this comes with several advantages.
Protein A purification is standard and, as needed, we use alternative resins such as Protein G, L, Kappa/Lambda-Select or anti-IgG-CH1. An additional size exclusion chromatography (SEC) purification step can be added. Please contact us for more details.
For new antibodies, our average timeline is between 6 and 7 weeks. With our standard services, we do guarantee 6-8 weeks from amino acid sequence to purified antibody and 5-6 weeks with our RUSH offering. If we have produced the antibody before, reproduction will take 1-2 weeks.
Recombinant antibody expression involves the artificial creation of monoclonal antibodies through genetic engineering and related methods. Genetically engineered antibodies hold significant value in scientific research due to their capability to identify specific antigenic sites on various molecules, such as drugs, hormones, microbial antigens, and cell receptors.