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Bispecific Antibodies: A Comprehensive Overview
BsAbs are a comparatively new and extremely promising class of antibodies. In this article, we provide an overview of bispecific antibodies, including their mechanism of action and expressions.
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Antibody-Dependent Cellular Cytotoxicity (ADCC) – Definition, Mechanism & Application
Antibody-dependent cellular cytotoxicity is a key process of the immune system’s arsenal to ward off cancerous cells and infections. We show you important definitions and the ADCC mechanism and key facts on ADCC antibodies in this post.
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Speed vs. Quality in Early Drug Development: Striking the Right Balance for Antibody Therapeutics
In drug development, speed without reproducibility risks costly setbacks. This article shows how high-quality antibody materials, early testing, and smart design enable faster, more reliable programs without compromising rigor.
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Why Promising Antibody Candidates Fail Before Clinical Trials – and How to Avoid It
Despite strong market growth, most antibody candidates fail early due to developability, pharmacokinetics, or immunogenicity issues. This article outlines key risks and strategies to de-risk development and speed the path from discovery to IND.
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Fast-Tracking Bispecific Antibody Development: What Can Go Wrong?
Bispecific antibodies hold great promise, but rushing development can trigger design and manufacturing risks. This article explores how smart strategies and expert partnerships accelerate bsAb programs without compromising quality.
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The Risks of Over-Promising in Early-Stage Biologics Development
In early biologics development, over-promising can derail programs and erode trust. This article explores the causes, consequences, and how data-driven planning safeguards progress and credibility.
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CHO cells – 7 facts about the cell line derived from the ovary of the Chinese hamster
Cells derived from animals like Chinese hamster ovary cells have been cultured and manipulated for use in pharmaceutical compounds for decades. They form the vital basis of a vast number of applications and are perfect tools for research and development.
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The history of antibodies
Due to the Corona pandemic, the term “antibody” has become one of the buzzwords of 2020/2021. The history of antibodies, also known as immunoglobulin, of course reaches back far further than the early months of 2020 – their meaning and importance has not only started gaining relevance with the outbreak of COVID-19.
